TY  - JOUR
PY  - 1997//
TI  - Caffeine self-administration in humans: 1. Efficacy of cola vehicle
JO  - Experimental and clinical psychopharmacology
A1  - Liguori, A.
A1  - Hughes, J. R.
A1  - Oliveto, A. H.
SP  - 286
EP  - 294
VL  - 5
IS  - 3
N2  - Eight exclusive cola drinkers in Experiment 1 (mean caffeine intake = 157 +/- 74 mg/day) and 16 drinkers of both cola and coffee in Experiment 2 (mean caffeine intake = 579 +/- 201 mg/day) underwent 6 independent, double-blind weekly trials. Each trial began with a randomized cross-over sampling period of 1 day of access to noncaffeinated cola and 1 day of access to caffeinated (33 mg/8 oz) cola. During the subsequent 1- or 2-day test period, participants had unlimited concurrent access to the 2 colas. Reliable caffeine self-administration occurred in 2 of 8 participants in Experiment 1 and in 4 of 16 participants in Experiment 2. Self-reported drowsiness, fatigue, and headache were higher when participants received only placebo colas in Experiment 2, but not Experiment 1. Caffeine self-administration via cola occurs both among people whose primary source of caffeine is cola and among those whose primary source of caffeine is coffee.<p /> <p>Language: en</p>
LA  - en
SN  - 1064-1297
UR  - http://dx.doi.org/
ID  - ref1
ER  -