TY  - JOUR
PY  - 1997//
TI  - Gas chromatographic examination of postmortem specimens after maprotiline intoxication
JO  - Forensic science international
A1  - Keller, T.
A1  - Zollinger, Ulrich
SP  - 117
EP  - 123
VL  - 88
IS  - 2
N2  - Ingestion of an unknown quantity of Ludiomil (maprotiline)-costed tablets in a suicide is described. Although maprotiline is known for over 20 years now, relatively few cases of intoxications due to maprotiline overdose have been reported. The authors report a new and quick method to analyze and determine maprotiline and N-desmethylmaprotiline concentration in body fluids and postmortem specimens. The analytes and an internal standard (amitriptyline) were extracted from alkalinized samples into ethyl acetate before GC-NPD analysis. The proposed method resulted in a rapid procedure most useful in cases of deliberate poisoning with the tetracyclic antidepressant drug Ludiomil.<p /> <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/
ID  - ref1
ER  -