TY  - JOUR
PY  - 1997//
TI  - Immunologic reactivity on one year follow-up of subjects without allergy to Hymenoptera stings
JO  - Asian Pacific journal of allergy and immunology
A1  - Ono, T.
A1  - Yoshida, Masatomo
A1  - Nakazono, N.
SP  - 81
EP  - 88
VL  - 15
IS  - 2
N2  - We studied Hymenoptera stings in 72 pest-control operators without any previous systemic reactions to Hymenoptera stings, and investigated their venom-specific IgE levels in serial specimens collected over one year. At the initial evaluation, venom-specific IgE was present in 25 (34.7%) of 72 pest-control operators, and venom-specific IgE titer significantly decreased as the time interval from the last sting increased (p < 0.001). In most cases, venom-specific IgE disappeared less than 3 years after the last sting. On the other hand, the ratio of subjects with positive CAP for venom-specific IgE was significantly increased with an elevation of total serum IgE level (p < 0.001). After the one year follow-up, venom-specific IgE titer in the 25 subjects with positive CAP decreased significantly (p = 0.026). Total serum IgE level modified the decline significantly (p = 0.011), but the time interval from the last sting did not. In elevated total IgE level (>250 IU/ml), the decline of venom-specific IgE tended to be slow.<p /> <p>Language: en</p>
LA  - en
SN  - 0125-877X
UR  - http://dx.doi.org/
ID  - ref1
ER  -