TY  - JOUR
PY  - 1997//
TI  - Fatal bupropion overdose
JO  - Journal of toxicology - clinical toxicology
A1  - Harris, C. R.
A1  - Gualtieri, J.
A1  - Stark, G.
SP  - 321
EP  - 324
VL  - 35
IS  - 3
N2  - BACKGROUND: Bupropion is a unique monocyclic antidepressant that has been known to cause seizures in high therapeutic doses and in acute overdoses. Death due to ingestion, however, is a rare occurrence. CASE REPORT: We report a case of a 26-year-old man who ingested 23 g bupropion, developed seizures and hypoxia, and presented in cardiac arrest. The patient was resuscitated in the emergency department, but died 4 d after supportive intensive care. CONCLUSIONS: Bupropion overdose may lead to recurrent seizures, hypoxia and death. Aggressive management of severe bupropion overdose is recommended.<p /> <p>Language: en</p>
LA  - en
SN  - 0731-3810
UR  - http://dx.doi.org/
ID  - ref1
ER  -