TY - JOUR PY - 1995// TI - Stress and alcohol: the moderating effect of chronic stress on the acute stress--intoxication relationship JO - Journal of studies on alcohol A1 - Breslin, F. C. A1 - Hayward, M. A1 - Baum, A. S. SP - 546 EP - 552 VL - 56 IS - 5 N2 - OBJECTIVE: The present study evaluated whether chronic stress levels moderated the impact of laboratory stressors on subjective and behavioral responses to alcohol. METHOD: Healthy volunteers (N = 60; 30 male) completed measures of background stress levels (e.g., major life events). In addition, subjects were exposed to two laboratory stressors (i.e., cold pressor or film stressor task) or a control condition after consuming a 0.7 g/kg dose of alcohol. RESULTS: Regression analyses showed that the combination of high background stress levels and exposure to a lab stressor reduced two measures of perceived intoxication (i.e., Sensation Scale, Visual Analog Intoxication Scale). CONCLUSIONS: These data are consistent with a biobehavioral model of alcohol use where acute and chronic stressors are associated with a diminished response to alcohol. The possible mechanisms that may underlie this sobering effect include stress-related cognitive deficits and situation specific tolerance associated with high chronic stress levels.
Language: en
LA - en SN - 0096-882X UR - http://dx.doi.org/ ID - ref1 ER -