TY  - JOUR
PY  - 1970//
TI  - Lateral hypothalamic control of killing: evidence for a cholinoceptive mechanism
JO  - Science
A1  - Smith, David E.
A1  - King, M. B.
A1  - Hoebel, B. G.
SP  - 900
EP  - 901
VL  - 167
IS  - 3919
N2  - In rats that would not ordinarily kill mice, lateral hypothalamic injection of crystalline carbachol, a cholinomimetic, elicited killing. Norepinephrine, amphetamine, serotonin, and sodium salts were ineffective at the same site. Carbachol was ineffective when injected into the medial, dorsal, or ventral hypothalamus. As additional evidence for a cholinoceptive mechanism, neostigmine elicited killing, and, in spontaneous killers, methyl atropine blocked it. The results indicate that the lateral hypothalamus contains a cholinoceptive component of an innate system that activates killing, and anticholinergic treatment can be used as a means of suppressing killing.<p /> <p>Language: en</p>
LA  - en
SN  - 0036-8075
UR  - http://dx.doi.org/
ID  - ref1
ER  -