TY  - JOUR
PY  - 2010//
TI  - Early childhood adversity and later hypertension: data from the World Mental Health Survey
JO  - Annals of clinical psychiatry
A1  - Stein, Dan J.
A1  - Scott, Kate
A1  - Haro Abad, Josep Maria
A1  - Aguilar-Gaxiola, Sergio
A1  - Alonso, Jordi
A1  - Angermeyer, Matthias
A1  - Demytteneare, Koen
A1  - de Girolamo, Giovanni
A1  - Iwata, Noboru
A1  - Posada-Villa, Jose
A1  - Kovess, Viviane
A1  - Lara, Carmen
A1  - Ormel, Johan
A1  - Kessler, Ronald C.
A1  - Von Korff, Michael
SP  - 19
EP  - 28
VL  - 22
IS  - 1
N2  - BACKGROUND: Although many studies have indicated that psychosocial factors contribute to hypertension, and that early childhood adversity is associated with long-term adverse mental and physical health sequelae, the association between early adversity and later hypertension is not well studied. METHOD: Data from 10 countries participating in the World Health Organization (WHO) World Mental Health (WHM) Surveys (N = 18,630) were analyzed to assess the relationship between childhood adversity and adult-onset hypertension, as ascertained by self-report. The potentially mediating effect of early-onset depression-anxiety disorders, as assessed by the WHM Survey version of the International Diagnostic Interview (WMH-CIDI), on the relationship between early adversity and hypertension was also examined. RESULTS: Two or more early childhood adversities, as well as early-onset depression-anxiety, were significantly associated with hypertension. A range of specific childhood adversities, as well as early-onset social phobia and panic/agoraphobia, were significantly associated with hypertension. In multivariate analyses, the presence of 3 or more childhood adversities was associated with hypertension, even when early-onset depression-anxiety or current depression-anxiety was included in the model. CONCLUSIONS: Although caution is required in the interpretation of self-report data on adult-onset hypertension, the results of this study further strengthen the evidence base regarding the role of psychosocial factors in the pathogenesis of hypertension.<p />  <p>Language: en</p>
LA  - en
SN  - 1040-1237
UR  - http://dx.doi.org/
ID  - ref1
ER  -