TY  - JOUR
PY  - 1996//
TI  - Use of fluoxetine to treat dominance aggression in dogs
JO  - Journal of the American Veterinary Medical Association
A1  - Dodman, N. H.
A1  - Donnelly, R.
A1  - Shuster, L.
A1  - Mertens, P.
A1  - Rand, W.
A1  - Miczek, Klaus A.
SP  - 1585
EP  - 1587
VL  - 209
IS  - 9
N2  - OBJECTIVE: To evaluate fluoxetine for the treatment of owner-directed dominance aggression in dogs. DESIGN: Prospective study. ANIMALS: 9 dogs of various breeds, ages, and either sex determined to have owner-directed dominance aggression. PROCEDURE: Placebo and fluoxetine (1 mg/kg of body weight) were compared for the treatment of owner-directed dominance aggression in a single-blind crossover study. Owners were instructed to record aggressive and nonaggressive responses of their dogs daily on a canine-overt aggression chart for the 5-week duration of the study. Total aggression scores (linear and geometric) were calculated for each week of the study. The frequency of individual responses was also analyzed independently. RESULTS: Fluoxetine resulted in a significant (P = 0.01) reduction in owner-directed dominance aggression after 3 weeks of treatment. No particular aggressive response accounted for the overall reduction in aggression. CLINICAL IMPLICATIONS: Fluoxetine may be useful in the management of dominance aggression in dogs.<p /> <p>Language: en</p>
LA  - en
SN  - 0003-1488
UR  - http://dx.doi.org/
ID  - ref1
ER  -