TY  - JOUR
PY  - 2001//
TI  - Tryptophan depletion increases aggression in women during the premenstrual phase
JO  - Psychopharmacology
A1  - Bond, Alyson J.
A1  - Wingrove, J.
A1  - Critchlow, D. G.
SP  - 477
EP  - 480
VL  - 156
IS  - 4
N2  - RATIONALE: Reducing serotonin by the method of tryptophan depletion (TD) has led to increased aggression but experimental studies have not used female subjects. OBJECTIVE: To evaluate the effects of TD on aggression in women in the late luteal phase of their menstrual cycle. METHODS: Healthy women were recruited and randomly assigned to an amino acid drink either depleted or with a balanced amount of tryptophan. At 4.5 h later, they competed on the competitive reaction time task. RESULTS: Women who had received the TD drink showed more behavioural aggression in response to provocation. CONCLUSION: Decreased serotonergic neurotransmission increases aggression in women as well as men.<p /> <p>Language: en</p>
LA  - en
SN  - 0033-3158
UR  - http://dx.doi.org/
ID  - ref1
ER  -