TY  - JOUR
PY  - 2001//
TI  - Anterior cingulate N-acetylaspartate/creatine ratios during clonidine treatment in a maltreated child with posttraumatic stress disorder
JO  - Journal of child and adolescent psychopharmacology
A1  - De Bellis, M. D.
A1  - Keshavan, M. S.
A1  - Harenski, Keith A.
SP  - 311
EP  - 316
VL  - 11
IS  - 3
N2  - Posttraumatic stress disorder in maltreated children is associated with dysregulation of biological stress systems, adverse brain development, and neuronal loss in the anterior cingulate region of the medial prefrontal cortex. A maltreated boy with posttraumatic stress disorder was followed prospectively using single voxel proton magnetic resonance spectroscopy measures of anterior cingulate N-acetylaspartate/creatine ratios, a marker of neural integrity. N-acetylaspartate/creatine ratios increased, and sleep measures improved upon symptom remission.<p /> <p>Language: en</p>
LA  - en
SN  - 1044-5463
UR  - http://dx.doi.org/10.1089/10445460152595649
ID  - ref1
ER  -