TY  - JOUR
PY  - 1999//
TI  - Assessment of the pulmonary toxicity of inhaled gases and particles with physicochemical methods
JO  - International journal of occupational safety and ergonomics
A1  - Sosnowski, T. R.
A1  - Podgorski, A.
SP  - 431
EP  - 447
VL  - 5
IS  - 3
N2  - Physicochemical techniques used for evaluating the pulmonary surfactant (PS) quality are discussed as methods useful in assessing toxicity of inhaled gases and particles. Two standard devices, Langmuir-Wilhelmy film balance and pulsating bubble apparatus, are presented in detail, and the measured results of interaction between sulfuric acid and 2 models of PS materials are analyzed. The evident decrease in surface activity of the pulmonary surfactant after its contact with the acid at concentrations approaching 0.001 M may be considered as an indicator of the adverse effect, which can result in several health problems. The presented approach can be used as a method of assessing pulmonary toxicity of any substances present in the breathing air.<p />  <p>Language: en</p>
LA  - en
SN  - 1080-3548
UR  - http://dx.doi.org/
ID  - ref1
ER  -