TY - JOUR PY - 2003// TI - Alterations in brain activation in posttraumatic stress disorder patients with severe hyperarousal symptoms and impulsive aggressiveness JO - European archives of psychiatry and clinical neuroscience A1 - Pavic, Ladislav A1 - Gregurek, Rudolf A1 - Petrović, Ratimir A1 - Petrović, Damir A1 - Varda, Robert A1 - Vukusić, Herman A1 - Crnković-Marković, Suncana SP - 80 EP - 83 VL - 253 IS - 2 N2 - OBJECTIVE: We wanted to assess possible alterations in brain activation in PTSD patients with severe hyperarousal symptoms and impulsive aggressiveness. METHOD: 25 Croatian War (1991-1995) veterans with combat-related PTSD with severe hyperarousal symptoms and impulsive aggressiveness were assessed for possible alterations in cerebral blood flow in single photon emission computed tomography brain scans. RESULTS: Increased regional cerebral blood flow in projection area of nucleus accumbens was found in 13 of 25 subjects, and for all in the dominant brain hemisphere. DISCUSSION: We believe that at least some of PTSD symptoms, and especially the impulsive aggression, can be associated with increased regional cerebral blood flow in the projection area of nucleus accumbens.
Language: en
LA - en SN - 0940-1334 UR - http://dx.doi.org/10.1007/s00406-003-0411-z ID - ref1 ER -