TY - JOUR PY - 2008// TI - Neurotropic effects of L-lysine in formation of pain-induced behavior JO - Bulletin of experimental biology and medicine A1 - Severyanova, L. A. A1 - Dolgintsev, M. E. A1 - Bobyntsev, I. I. A1 - Kryukov, A. A. SP - 592 EP - 594 VL - 145 IS - 5 N2 - In experiments on Wistar rats L-lysine (0.15, 0.5, 1.5, 5.0, 15.0, and 50.0 microg/kg intraperitoneally) exhibited a dose-dependent algic effect during electrocutaneous stimulation of the tail and dose-dependent effects in aggressive defense behavior caused by electrical painful stimulation of paws. It was found that the effect of L-lysine depended on situation determining the predominance of defense or aggression, rather than on the intensity of painful stimulation.

Language: en

LA - en SN - 0007-4888 UR - http://dx.doi.org/ ID - ref1 ER -