TY  - JOUR
PY  - 1999//
TI  - Low blood cholesterol and low platelet serotonin levels in violent suicide attempters
JO  - Biological psychiatry
A1  - Alvarez, J. C.
A1  - Cremniter, D.
A1  - Lesieur, P.
A1  - Gregoire, A.
A1  - Gilton, A.
A1  - Macquin-Mavier, I.
A1  - Jarreau, C.
A1  - Spreux-Varoquaux, O.
SP  - 1066
EP  - 1069
VL  - 45
IS  - 8
N2  - AIM OF THE STUDY: This study investigated the possible connection between serum cholesterol levels and platelet serotonin (5-HT) content in violent suicide attempters and matched controls. METHODS: Blood samples for cholesterol and platelet 5-HT levels were obtained from 17 drug-free patients within 3 days after the suicide attempt. RESULTS: Serum cholesterol and platelet 5-HT levels in the suicide attempters were significantly lower than in the controls; however, we did not find any significant correlation between these two variables. Indeed, three clinical dimensions are present in this patient group: suicidality, violence, and impulsiveness. Because we did not find a difference in cholesterol and platelet 5-HT levels between impulsive and nonimpulsive patients, these two indexes may more reflect the dimension of suicidality and/or violence. CONCLUSIONS: Further investigation is necessary to study the dependence of these two peripheral abnormalities within the context of violent suicidal behavior.<p /> <p>Language: en</p>
LA  - en
SN  - 0006-3223
UR  - http://dx.doi.org/
ID  - ref1
ER  -