TY  - JOUR
PY  - 1999//
TI  - Characterization of the defensive nature of kindling-induced emotionality
JO  - Behavioral neuroscience
A1  - Kalynchuk, L. E.
A1  - Pinel, J. P.
A1  - Treit, D.
SP  - 766
EP  - 775
VL  - 113
IS  - 4
N2  - Long-term amygdala kindling produces substantial changes in emotional behavior in rats. The purpose of these experiments was to determine whether kindling-induced emotionality is fundamentally defensive or aggressive in nature. In Experiment 1, amygdala-kindled rats tested as intruders in a resident-intruder paradigm preferred an active defense strategy (i.e., defensive upright stance, jump attacks), whereas the sham-stimulated rats preferred a passive defense strategy (i.e., freezing). In Experiment 2, amygdala-kindled rats explored an unfamiliar open field significantly less than did the sham-stimulated rats, and they were significantly more resistant to capture from the unfamiliar open field than were the sham-stimulated rats. In contrast, there were no significant differences between the kindled and sham-stimulated rats in resistance to capture from their home cages. These results suggest that the emotionality produced by long-term amygdala kindling is fundamentally defensive in nature.<p /> <p>Language: en</p>
LA  - en
SN  - 0735-7044
UR  - http://dx.doi.org/
ID  - ref1
ER  -