TY - JOUR PY - 2012// TI - Temperaments mediate suicide risk and psychopathology among patients with bipolar disorders JO - Comprehensive psychiatry A1 - Pompili, Maurizio A1 - Rihmer, Zoltan A1 - Akiskal, Hagop S. A1 - Amore, Mario A1 - Gonda, Xenia A1 - Innamorati, Marco A1 - Lester, David A1 - Perugi, Giulio A1 - Serafini, Gianluca A1 - Telesforo, Ludovica A1 - Tatarelli, Roberto A1 - Girardi, Paolo SP - 280 EP - 285 VL - 53 IS - 3 N2 - BACKGROUND: Several studies have demonstrated that bipolar II (BD-II) disorder represents a quite common, distinct form of major mood disorders that should be separated from bipolar I (BD-I) disorder. The aims of this cross-sectional study were to assess temperament and clinical differences between patients with BD-I and BD-II disorders and to assess whether temperament traits are good predictors of hopelessness in patients with bipolar disorder, a variable highly associated with suicidal behavior and ideation. METHOD: Participants were 216 consecutive inpatients (97 men and 119 women) with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR), BD who were admitted to the Sant'Andrea Hospital's psychiatric ward in Rome (Italy). Patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire, the Beck Hopelessness Scale (BHS), the Mini International Neuropsychiatric Interview (MINI), and the Gotland Scale of Male Depression. RESULTS: Patients with BD-II had higher scores on the BHS (9.78 ± 5.37 vs 6.87 ± 4.69; t(143.59) = -3.94; P < .001) than patients with BD-I. Hopelessness was associated with the individual pattern of temperament traits (ie, the relative balance of hyperthymic vs cyclothymic-irritable-anxious-dysthmic). Furthermore, patients with higher hopelessness (compared with those with lower levels of hopelessness) reported more frequently moderate to severe depression (87.1% vs 38.9%; P < .001) and higher MINI suicidal risk. CONCLUSION: Temperaments are important predictors both of suicide risk and psychopathology and may be used in clinical practice for better delivery of appropriate care to patients with bipolar disorders.
Language: en
LA - en SN - 0010-440X UR - http://dx.doi.org/10.1016/j.comppsych.2011.04.004 ID - ref1 ER -