TY  - JOUR
PY  - 1996//
TI  - A case of aconitine poisoning with analysis of aconitine alkaloids by GC/SIM
JO  - Forensic science international
A1  - Yoshioka, N.
A1  - Gonmori, K.
A1  - Tagashira, A.
A1  - Boonhooi, O.
A1  - Hayashi, Miwa
A1  - Saito, Yasuhiko
A1  - Mizugaki, M.
SP  - 117
EP  - 123
VL  - 81
IS  - 2-3
N2  - Described here is a fatal case of accidental aconitine poisoning following the ingestion of aconite, Torikabuto, mistaken for an edible grass, Momijigasa. A 61-year-old man developed symptoms of nausea, diarrhea, and discomfort of the body about 2 h after the ingestion and was taken to an emergency room. Resuscitation and antiarrhythmic drugs were ineffective, and ventricular tachycardia and fibrillation developed and lasted for 6 h. He was transferred to a coronary care unit and complete sinus rhythm was obtained on an electrocardiogram 30 h after his admission. The patient fell into a coma and died of brain edema diagnosed by CT on the 6th day. Consent for autopsy was denied by the family but was given for gas chromatography/selected ion monitoring (GC/SIM) to analyze the toxicity of aconitine alkaloids in the blood and the urine. Only a faint amount of jesaconitine was detected, while aconitine, mesaconitine and hypaconitine were not detectable in the blood 24 h after ingestion. On the other hand, aconitine and its related alkaloids such as mesaconitine, jesaconitine, and hypaconitine were clearly detected in the urine.<p /> <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/
ID  - ref1
ER  -