TY - JOUR PY - 1996// TI - Visual evoked potentials in low blood alcohol concentrations JO - Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft A1 - Behrendt, S. A1 - Kaatsch, H. J. A1 - Schwinger, R. SP - 367 EP - 370 VL - 93 IS - 4 N2 - BACKGROUND: Both the acute toxic effects of ethanol on the central nervous system and the effects of chronic alcohol consumption on the optic nerve (tobacco-alcohol amblyopia) are well known. We investigated the acute effect of low blood alcohol concentrations on visual evoked potentials. MATERIALS AND METHODS: A pattern VEP (stimulation by TV monitor, alternating chequerboard patterns, 45', 2 Hz, contrast 90%) was performed in ten healthy volunteers in sober condition and 0, 30, 60, 90 and 120 min following ingestion of 1 g/kg body weight ethanol (resulting in a blood alcohol concentration of 0.8-1.1%). Blood samples were drawn from the cubital vein simultaneously with each recording to determine blood alcohol concentration. RESULTS: Neither peak latencies nor amplitudes showed significant changes related to blood alcohol concentration. CONCLUSION: No acute impairment of the optic nerve caused by ingestion of low doses of alcohol could be found using pattern VEP.

Language: de

LA - de SN - 0941-293X UR - http://dx.doi.org/ ID - ref1 ER -