TY  - JOUR
PY  - 2011//
TI  - Combining the categorical and the dimensional perspective in a diagnostic map of psychotic disorders
JO  - European archives of psychiatry and clinical neuroscience
A1  - Läge, Damian
A1  - Egli, Samy
A1  - Riedel, Michael
A1  - Strauss, Anton
A1  - Moller, Hans-Jurgen
SP  - 3
EP  - 10
VL  - 261
IS  - 1
N2  - We introduce a diagnostic map that was calculated by robust non-metric multidimensional scaling based on AMDP symptom profiles of patients with schizophrenic and affective disorders to demonstrate a possibility to combine the categorical and the dimensional perspective at the same time. In the diagnostic map, a manic, a depressive, and a non-affective cluster clearly emerged. At the same time, the mania dimension (r = 0.82), the depression dimension (r = 0.68), and the apathy dimension (r = 0.74) showed high multiple regression values in the map. We found substantial overlaps of the diagnostic groups with regard to the affective spectrum but irrespective of the ICD-10 classification. Within this sample, we found the association and quality of mood symptoms to be a structuring principle in a diagnostic map. We demonstrate that this approach represents a promising way of combining the categorical and the dimensional perspective. As a practical implementation of these findings, a multidimensional diagnostic map could serve as an automated diagnostic tool based on psychopathological symptom profiles.<p />  <p>Language: en</p>
LA  - en
SN  - 0940-1334
UR  - http://dx.doi.org/10.1007/s00406-010-0125-y
ID  - ref1
ER  -