TY  - JOUR
PY  - 1999//
TI  - Psychotic illness after prenatal exposure to the 1953 Dutch Flood Disaster
JO  - Schizophrenia Research
A1  - Selten, J. P.
A1  - van der Graaf, Y.
A1  - van Duursen, R.
A1  - Gispen-de Wied, C. C.
A1  - Kahn, R. S.
SP  - 243
EP  - 245
VL  - 35
IS  - 3
N2  - We tested the hypothesis that maternal stress during pregnancy increases the risk of non-affective psychosis for the child. The concept of non-affective psychosis includes the ICD categories schizophrenic disorder, paranoid state and other non-organic psychosis. Data from the Dutch Psychiatric Registry were examined for an effect of the Flood Disaster of 1 February 1953. On this day, a gale caused a flood in the South-west of The Netherlands and 1835 people perished. Our study concerned the 19 villages where mortality exceeded 0.25%. The risk of non-affective psychosis for the cohort born in the period February-October 1953 was compared to the risks for the cohorts born in the corresponding periods of the previous and subsequent 2 years. The relative risk of non-affective psychosis for those exposed during gestation was 1.8 [95% Confidence Interval (CI): 0.9-3.5]. Thus, our study failed to demonstrate a significant association between prenatal exposure to maternal stress and risk of non-affective psychosis. The possible explanations for this finding are discussed.<p /> <p>Language: en</p>
LA  - en
SN  - 0920-9964
UR  - http://dx.doi.org/
ID  - ref1
ER  -