TY  - JOUR
PY  - 1998//
TI  - Confirmation of oleander poisoning by HPLC/MS
JO  - International journal of legal medicine
A1  - Tracqui, A.
A1  - Kintz, P.
A1  - Branche, F.
A1  - Ludes, Bertrand
SP  - 32
EP  - 34
VL  - 111
IS  - 1
N2  - A non-fatal case of Nerium oleander (common oleander) self-poisoning in a 45-year-old female is presented. Initial symptoms were nausea and vomiting, abdominal pain, phosphenes, cardiovascular shock and sinus brady-cardia. Blood and urine were assayed for oleandrin, the major cardiac glycoside of N. oleander, using a highly specific HPLC/MS procedure. The blood concentration of oleandrin at admission was 1.1 ng/ml. This is the first report of an oleander intoxication ascertained by the mass spectrometric identification of oleandrin in blood. HPLC/MS appears to be the method of choice for the forensic-toxicological investigation of poisonings by cardiac glycosides.<p /> <p>Language: en</p>
LA  - en
SN  - 0937-9827
UR  - http://dx.doi.org/
ID  - ref1
ER  -