TY  - JOUR
PY  - 1992//
TI  - Massive strychnine intoxication: serial blood levels in a fatal case
JO  - Journal of toxicology - clinical toxicology
A1  - Heiser, J. M.
A1  - Daya, M. R.
A1  - Magnussen, A. R.
A1  - Norton, R. L.
A1  - Spyker, D. A.
A1  - Allen, D. W.
A1  - Krasselt, W.
SP  - 269
EP  - 283
VL  - 30
IS  - 2
N2  - A fatal case of strychnine intoxication is reported. The patient expired despite early aggressive management and prevention of metabolic complications. Serial blood levels are reported. In contrast to a previous report describing first order elimination kinetics, our data suggest that strychnine follows Michaelis-Menton elimination kinetics. The case illustrates the rapid, dramatic course of severe strychnine ingestions. A review of the toxicokinetics, mechanism of action and treatment of strychnine intoxication follows.<p /> <p>Language: en</p>
LA  - en
SN  - 0731-3810
UR  - http://dx.doi.org/
ID  - ref1
ER  -