TY  - JOUR
PY  - 1991//
TI  - Subacute arsenic poisoning
JO  - Annales Francaises d'Anesthesie et de Reanimation
A1  - Ghariani, M.
A1  - Adrien, M. L.
A1  - Raucoules, M.
A1  - Bayle, J.
A1  - Jacomet, Y.
A1  - Grimaud, D.
SP  - 304
EP  - 307
VL  - 10
IS  - 3
N2  - A cas is reported of a 23-year-old man who voluntarily took a massive dose of arsenic (at least 8 g). In spite of the ingested amount and the acute nature of the poisoning, the patient survived 8 days. Gastrointestinal, neurologic and cardiac features were predominant including nausea, vomiting, choleroid diarrhoea, encephalopathy, peripheral neuropathy, and finally a fatal toxic cardiomyopathy. Metabolic acidosis, moderate cytolysis and an anticoagulant effect were also observed. This unique characteristic was partly due to a circulating anticoagulant with prothrombinase activity, as well as direct antivitamin K activity. Postmortem examination revealed: a congestive oesophagitis; a necrosing gastritis involving all the stomach wall; diffuse hepatic steatosis; skin lesions with vascular congestion and dermoepidermal detachment; discrete subepicardial congestive lesions. Arsenic was found in all tissues.<p /> <p>Language: fr</p>
LA  - fr
SN  - 0750-7658
UR  - http://dx.doi.org/
ID  - ref1
ER  -