TY - JOUR PY - 1991// TI - Temporal segmentation of response speed in depression: neuro-electrophysiological approaches JO - Progress in neuro-psychopharmacology and biological psychiatry A1 - Knott, V. J. A1 - Lapierre, Y. D. SP - 249 EP - 255 VL - 15 IS - 2 N2 - 1. Depressive psychomotor retardation, as observed by delayed reaction times (RT), may be related to a slowing in information processing speed. 2. Two separate studies compared indices of information processing speed in depressed patients and non-clinical controls by segmenting behavioral RT with brain event-related potentials (ERPs) and electromyographic (EMG) responses. 3. In Study I, slower behavioral RTs in depression were concomitant with slower central processing times (CPT) but not motor execution times (MET). 4. In Study II, P165, a putative early cognitive ERP related to 'stimulus evaluation time', was found to be slower but within normal range in depressed patients.
Language: en
LA - en SN - 0278-5846 UR - http://dx.doi.org/ ID - ref1 ER -