TY  - JOUR
PY  - 2011//
TI  - Iron and acetaminophen a fatal combination?
JO  - Transplant international
A1  - Audimoolam, Vinod K.
A1  - Wendon, Julia
A1  - Bernal, William
A1  - Heaton, Nigel
A1  - O'Grady, John
A1  - Auzinger, Georg
SP  - e85
EP  - 8
VL  - 24
IS  - 10
N2  - Intentional iron overdose in adults is uncommon. Clinical consequences are variable and depend on the quantity of iron ingested and the delay to treatment. Severe iron overdose can lead to multi-organ failure and acute hepatic necrosis. Here, we report three cases of polypharmacy overdose including iron resulting in acute liver failure. Despite maximum supportive care including liver transplantation in two cases, all patients died. Iron poisoning may have an additive toxic effect in drug-induced acute liver failure and worsen outcome.<p />  <p>Language: en</p>
LA  - en
SN  - 0934-0874
UR  - http://dx.doi.org/10.1111/j.1432-2277.2011.01322.x
ID  - ref1
ER  -