TY - JOUR PY - 1979// TI - Immunoassay of macrophage stimulating alpha 2 SB (surface binding) glycoprotein in pig plasma following missile trauma JO - Acta chirurgica Scandinavica Supplementum A1 - Berghem, L. A1 - Ahlgren, T. A1 - Lahnborg, G. SP - 239 EP - 244 VL - 489 IS - N2 - Pigs were subjected to a standardized missile trauma in the thigh and plasma samples were collected at various times after trauma. The plasma level of an opsonic alpha 2 SB (surface binding) glycoprotein related to macrophage phagocytosis was determined by an agglutination assay using 125I-labelled gelatin particles. The results indicated a transient but significance decrease (p less than 0.01) in the plasma agglutination activity after trauma reflecting a deficiency in plasma alpha 2 SB glycoprotein. One non-surviving animal showed a persistent decrease in the plasma level of alpha 2 SB glycoprotein, while the surviving animals showed a normalization indicating that this agglutination assay may have prognostic value during the course of posttraumatic therapy.
Language: en
LA - en SN - 0301-1860 UR - http://dx.doi.org/ ID - ref1 ER -