TY  - JOUR
PY  - 2011//
TI  - Pesticidal suicide: Adult fatal rotenone poisoning
JO  - Journal of forensic and legal medicine
A1  - Patel, Freddy
SP  - 340
EP  - 342
VL  - 18
IS  - 7
N2  - Rotenone is a pesticide and a piscicide derived from the derris root. The mechanism for the cytotoxicity is at mitochondrial level affecting cellular respiration. A suicide by rotenone poisoning in an adult is described. An innovative laboratory methodology was developed for the principal requirement of the Coroner to determine a positive or negative result to assist in the investigation of the death. The antemortem concentrations detected were 4.05 ng/ml [0.00405 ppm] in the blood and 0.55 ng/ml [0.00055 ppm] in the serum. Toxicity in human is rare and therefore the interpretation of the toxicology results is complicated by the unavailability of a data bank. The cause of death was attributed to rotenone toxicity based on the circumstantial evidence and expert pathological opinion on a balance of probability acceptable under the Coroners Act 1988 and Coroners Rules 1984 in England and Wales. The forensic clinicopathology of rotenone toxicity is discussed.<p />  <p>Language: en</p>
LA  - en
SN  - 1752-928X
UR  - http://dx.doi.org/10.1016/j.jflm.2011.06.014
ID  - ref1
ER  -