TY - JOUR PY - 1990// TI - Quantitative studies of mast cell proliferation at the wound edge --rate of DNA synthesis in intravital and postmortem biopsy JO - Beitrage zur Gerichtlichen Medizin A1 - Oehmichen, M. A1 - Cröpelin, A. A1 - Schmidt, V. SP - 271 EP - 276 VL - 48 IS - N2 - The number of DNA synthesizing mast cells in experimental induced wounds was calculated using bromodeoxyuridine as a DNA marker and naphthol AS-D chloroacetate esterase as a mast cell marker. After different survival times, specimens of the wound edge were taken before death and 24 hs after death. At a survival time of 48 hs in vital biopsy the number of DNA synthesizing mast cells peaked, at 72 hs and fell after a period of 8 days. Even though an identical kinetic course was demonstrable in cases of postmortal biopsies the percentage at each survival period was significantly lower than in vital biopsies.

Language: de

LA - de SN - 0067-5016 UR - http://dx.doi.org/ ID - ref1 ER -