TY  - JOUR
PY  - 1982//
TI  - Liver damage caused by drugs
JO  - Deutsche Zeitschrift für Verdauungs- und Stoffwechselkrankheiten
A1  - Dölle, W.
SP  - 237
EP  - 244
VL  - 42
IS  - 6
N2  - Drug injury of the liver presents as I. functional disorder without jaundice; 2. predominant cholostatic disease; 3. predominant hepatitic disease; 4. a combination of 2 und 3.--A predictable dose related direct toxic injury can be differentiated from an unpredictable dose independent indirect injury mostly of the hypersensitivity type. Special varieties are severe fatty liver, peliosis, Budd-Chiari-Syndrome, liver tumors and granulomas. The diagnosis can be proven by reexposition or better--by the in vitro lymphocyte stimulation test. --There is no specific treatment apart from stopping the responsible drug. Prognosis is good but in some cases a chronic course develops presenting as chronic aggressive hepatitis or cirrhosis.<p /> <p>Language: de</p>
LA  - de
SN  - 0012-1053
UR  - http://dx.doi.org/
ID  - ref1
ER  -