TY - JOUR PY - 1983// TI - Residual effects of flurazepam and brotizolam on psychomotor performance JO - British journal of clinical pharmacology A1 - Krueger, H. A1 - Müller-Limmroth, W. SP - 347S EP - 351S VL - 16 IS - Suppl 2 N2 - Residual effects of brotizolam (0.25 mg) and flurazepam (30 mg) were studied in healthy young adults. Performance and subjective assessments were observed from 7 to 8 h after overnight ingestion, and effects were compared with that of placebo. Visuo-motor coordination, visuo-mental processing time, visuo-motor reaction time and reading errors were not impaired with brotizolam. There were residual effects with 30 mg flurazepam. Visuo-motor coordination, visuo-mental processing time, visuo-motor reaction time, and reading errors were impaired compared with placebo and 0.25 mg brotizolam. Subjective assessments of performance correlated with measured performance. There was a decrease with flurazepam (visuo-motor coordination and visuo-mental processing time) compared with placebo.
Language: en
LA - en SN - 0306-5251 UR - http://dx.doi.org/ ID - ref1 ER -