TY - JOUR PY - 1983// TI - Effect of amphetamine on saccadic and smooth pursuit eye movements JO - Psychopharmacology A1 - Tedeschi, G. A1 - Bittencourt, P. R. A1 - Smith, A. T. A1 - Richens, A. SP - 190 EP - 192 VL - 79 IS - 2-3 N2 - Healthy volunteers received single oral or intravenous doses of d-amphetamine sulphate (15 mg) and placebo in a double blind randomized design. Peak velocity of horizontal saccadic eye movements, saccade duration, saccade reaction time and smooth pursuit velocity were measured at intervals up to 1 h (IV) and 6 h (oral) after drug administration. Amphetamine produced no significant effect on saccadic and smooth-pursuit eye movements after oral administration. However, intravenous amphetamine abolished the effect of fatigue on saccadic movements and significantly (P less than 0.01) shortened saccadic reaction time.
Language: en
LA - en SN - 0033-3158 UR - http://dx.doi.org/ ID - ref1 ER -