TY - JOUR PY - 1983// TI - Preliminary studies on the venom of the colubrid snake Rhabdophis subminatus (red-necked keelback) JO - Toxicon: Journal of the International Society on Toxinology A1 - Ferlan, I. A1 - Ferlan, A. A1 - King, T. A1 - Russell, F. E. SP - 570 EP - 574 VL - 21 IS - 4 N2 - Following the bite by Rhabdophis subminatus, preliminary studies were instituted on its venom to determine the mechanism of the clinical poisoning. A method for milking these snakes is presented. The i.v. LD50 in mice was 1.29 mg/kg. Three peaks were obtained on Sephadex G-100 and although none were lethal by themselves, a combination of two of the peaks produced immediate death in mice. The venom had no phosphodiesterase, fibrinolytic or thrombin-like activities, but it did have some phospholipase activity. Further biochemical and pharmacological studies are in progress.

Language: en

LA - en SN - 0041-0101 UR - http://dx.doi.org/ ID - ref1 ER -