TY  - JOUR
PY  - 1984//
TI  - The effects of phencyclidine on spontaneous aggressive behavior in the rat
JO  - Biological psychiatry
A1  - Russell, J. W.
A1  - Greenberg, B. D.
A1  - Segal, D. S.
SP  - 195
EP  - 202
VL  - 19
IS  - 2
N2  - Phencyclidine induced dose-related alterations in the pattern of spontaneous aggressive behavior in pairs of rats, in which only one animal of each pair was drug-treated. At the lowest dose tested (0.25 mg/kg, sc), phencyclidine produced attacks by the drug-treated animal and a corresponding increase in submissive behavior by the untreated partner, as well as an increase in boxing behavior by both animals. In contrast, the highest dose of phencyclidine tested (1.0 mg/kg, sc) elicited attacks and allogrooming by the untreated animal. The low dose effect is interpreted as the result of phencyclidine-induced distortion in perception of social cues, while the high dose effect may be due to a general disruption in social communication by ataxia in the phencyclidine-treated animal.<p /> <p>Language: en</p>
LA  - en
SN  - 0006-3223
UR  - http://dx.doi.org/
ID  - ref1
ER  -