TY  - JOUR
PY  - 1975//
TI  - Acute renal failure following snakebite
JO  - American journal of tropical medicine and hygiene
A1  - Chugh, K. S.
A1  - Aikat, B. K.
A1  - Sharma, B. K.
A1  - Dash, S. C.
A1  - Mathew, M. T.
A1  - Das, K. C.
SP  - 692
EP  - 697
VL  - 24
IS  - 4
N2  - Eight patients with acute renal failure following snakebite were studied. Intravascular hemolysis and disseminated intravascular coagulation contributed to the development of acute renal failure in 6 patients. Direct nephrotoxicity causing acute renal failure is postulated in 2 patients, 1 of whom also revealed evidence of mild, disseminated intravascular coagulation. Three patients had histopathological lesions of acute symmetrical cortical necrosis and 3 had acute tubular necrosis. In 1 patient with acute tubular necrosis, in whom direct nephrotoxicity seemed to be responsible for renal failure, the striking histological feature was a uniform debasement and disappearance of tubular epithelium. In 2 patients with a clinical course of acute tubular necrosis, histological lesions could not be documented. All the 5 patients with acute tubular necrosis regained full recovery of renal function, 3 of them with the help of dialysis and 2 with conservative management. None of the 3 patients with acute cortical necrosis survived in spite of intermittent dialysis therapy.<p /> <p>Language: en</p>
LA  - en
SN  - 0002-9637
UR  - http://dx.doi.org/
ID  - ref1
ER  -