TY  - JOUR
PY  - 1975//
TI  - An investigation of recurrent pine oil poisoning in an infant by the use of gas chromatographic-mass spectrometric methods
JO  - Journal of pediatrics
A1  - Horning, M. G.
A1  - Harvey, D. J.
A1  - Butler, C. M.
A1  - Hill, L. Leighton
A1  - Barer, J.
A1  - Hill, R. M.
SP  - 115
EP  - 118
VL  - 87
IS  - 1
N2  - An 18-month-old infant required six hospital admissions in a period of six months for episodes consisting of coughing, respiratory depression, hematemesis, coma, dehydration, and lesions about the mouth. A negative history of ingestion of toxins was repeatedly obtained from the family and two home inspection by the local Health Department failed to identify potential toxins. Metabolic work-up was entirely negative. Utilizing methods of GC-MS, metabolites of a-terpineol were isolated from infant urine on two admissions to the hospital. These metabolites were confirmed by mass spectrometry to be the same metabolites excreted by Sprague-Dawley rats injected with a-terpineol or pine oil. The child had no additional episodes after physical separation from the home environment.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-3476
UR  - http://dx.doi.org/
ID  - ref1
ER  -