TY - JOUR PY - 1976// TI - The dopamine hypothesis of schizophrenia: focus on the dopamine receptor JO - American journal of psychiatry A1 - Snyder, S. H. SP - 197 EP - 202 VL - 133 IS - 2 N2 - Alleviation of schizophrenic symptoms by phenothiazines and butyrophenones is associated with blockade of dopamine receptors, while exacerbation of symptoms by amphetamines appears to result from enhanced synaptic activity of dopamine and/or norepinephrine. The author suggests that biochemical labeling of the dopamine receptor with 3H-dopamine and 3H-haloperidol may clarify mechanisms of drug effects on the dopamine receptor.

Language: en

LA - en SN - 0002-953X UR - http://dx.doi.org/ ID - ref1 ER -