TY - JOUR PY - 2009// TI - Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008 JO - Toxins (Basel) A1 - de Haro, Luc A1 - Glaizal, Mathieu A1 - Tichadou, Lucia A1 - Blanc-Brisset, Ingrid A1 - Hayek-Lanthois, Maryvonne SP - 100 EP - 112 VL - 1 IS - 2 N2 - A retrospective case review study of viper envenomations collected by the Marseille's Poison Centre between 1996 and 2008 was performed. RESULTS: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. CONCLUSION: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity.
Language: en
LA - en SN - 2072-6651 UR - http://dx.doi.org/10.3390/toxins1020100 ID - ref1 ER -