TY  - JOUR
PY  - 2000//
TI  - Analytical method for the determination of strychnine in tissues by gas chromatography/mass spectrometry: two case reports
JO  - Forensic science international
A1  - Marques, Estela P.
A1  - Gil, F.
A1  - Proen'ca, P.
A1  - Monsanto, P.
A1  - Oliveira, M. F.
A1  - Castanheira, A.
A1  - Vieira, D. N.
SP  - 145
EP  - 152
VL  - 110
IS  - 2
N2  - This paper describes an analytical method for strychnine determination in biological samples by gas chromatography/mass spectrometry and their application in the investigation of two cases involving strychnine ingestion: A fatal case and a clinical one. The strychnine is isolated from biological samples using a liquid-liquid extraction procedure. The clean-up procedure is performed using an acid solution. Papaverine is used as internal standard in the quantification of strychnine. In the analysed specimens, the limits of quantification were 0.1 microg/ml or 0.1 microg/g. The recovery rate ranged from 75.0% to 98.7% and the coefficients of variation ranged from 4.8% to 10.5%.<p /> <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/
ID  - ref1
ER  -