TY  - JOUR
PY  - 2000//
TI  - Deterioration in quality of life following hip fracture: a prospective study
JO  - Osteoporosis international
A1  - Randell, A. G.
A1  - Nguyen, T. V.
A1  - Bhalerao, N.
A1  - Silverman, S. L.
A1  - Sambrook, P. N.
A1  - Eisman, J. A.
SP  - 460
EP  - 466
VL  - 11
IS  - 5
N2  - To examine longitudinal change in health-related quality of life (HRQoL) following hip fracture in elderly subjects, 32 patients with hip fractures and 29 sex-matched non-fracture control subjects (mean +/- SD age 82 +/- 8 and 86 +/- 6 years respectively) were enrolled in a prospective, case-control study. Fracture subjects completed a generic questionnaire, Short Form 36 (SF-36), and a disease-targeted measure, the revised Osteoporosis Assessment Questionnaire (OPAQ2), on two separate occasions, within 1 week of fracture and 12-15 weeks after fracture. Controls completed both questionnaires on two occasions 12 weeks apart. SF-36 scores were significantly correlated with OPAQ2 in comparable domains of Physical Function (r = 0.76), General Health (r = 0.70) and Mental Health/Tension (r=0.86). Control subjects had stable scores with the OPAQ2 and SF-36. At 3 months after fracture there was a significant reduction in HRQoL in the SF-36 domains Physical Function (-51%), Vitality (-24%) and Social Function (-26%) and in the OPAQ2 domains Physical Function (-20%), Social Activity (-49%) and General Health (-24%). Hip fracture patients thus had a lower baseline HRQoL and experienced a significant deterioration in HRQoL after hip fracture on both the SF-36 and OPAQ2. HRQoL should be part of a comprehensive assessment of the costs of osteoporosis including fracture-associated morbidity.<p /> <p>Language: en</p>
LA  - en
SN  - 0937-941X
UR  - http://dx.doi.org/
ID  - ref1
ER  -