TY  - JOUR
PY  - 2001//
TI  - Acute isoniazid poisoning presenting convulsion and liver dysfunction
JO  - Japanese journal of toxicology
A1  - Kiyota, K.
A1  - Hamabe, Y.
SP  - 57
EP  - 60
VL  - 14
IS  - 1
N2  - A-19-year-old girl ingested 7.4 g of Isoniazid (INH) and 14.5 g of Ethambutol (EB) intentionally. She presented repetitive generalized convulsions with metabolic acidosis, treated with diazepam and 7.5 g of Pyridoxine (Vitamin B6). During day 4 and 5, liver dysfunction worsened and prothrombin time declined below 5%. She was treated with infusion of fresh frozen plasma and fully recovered on day 13. Serum concentration of INH and EB at 5 hours after ingestion was 7.6, 0.94 micrograms/ml respectively.<p /> <p>Language: ja</p>
LA  - ja
SN  - 0914-3777
UR  - http://dx.doi.org/
ID  - ref1
ER  -