TY - JOUR PY - 2001// TI - Effects of testosterone and clomiphene on spectral EEG and visual evoked response in a young man with posttraumatic epilepsy JO - International journal of neuroscience A1 - Tan, M. A1 - Tan, U. SP - 87 EP - 94 VL - 106 IS - 1-2 N2 - The effects of testosterone and clomiphene on epilepsy was studied in a young man with posttraumatic seizures. In the control period, digital EEG and visual evoked potentials (VEPs) were recorded under carbamazapine therapy. After testosterone (T), seizures lessened and almost disappeared; the theta, delta, alpha, and beta powers decreased; VEPs increased. After clomiphene, VEPs considerably increased in size; clinical picture slightly improved; EEG power spectrum remained unchanged. It was suggested that T may be beneficial for epilepsy treatment by suppressing the EEG synchronization (slow wave activity) and attenuating the entropy state of the epileptic brain.

Language: en

LA - en SN - 0020-7454 UR - http://dx.doi.org/ ID - ref1 ER -