TY - JOUR PY - 2001// TI - An EEG severity index of traumatic brain injury JO - Journal of neuropsychiatry and clinical neurosciences A1 - Thatcher, R. W. A1 - North, D. M. A1 - Curtin, R. T. A1 - Walker, R. A. A1 - Biver, C. J. A1 - Gomez, J. F. A1 - Salazar, Andres M. SP - 77 EP - 87 VL - 13 IS - 1 N2 - EEG spectral analyses were conducted from 19 scalp locations for patients with mild (n=40), moderate (n=25), and severe (n=43) traumatic brain injury (TBI), 15 days to 4 years after injury. Severity of TBI was judged by emergency hospital admission records (Glasgow Coma Score and duration of coma and amnesia). Highest-loading EEG variables on each factor that differed significantly between severe and mild TBI by univariate t-test were entered into a multivariate discriminant analysis, yielding 16 variables. Discriminant analysis between mild and severe TBI groups showed classification accuracy of 96.39%, sensitivity 95.45%, and specificity 97.44%. The EEG discriminant score also measured intermediate severity in moderate TBI patients. Results were cross-validated in 503 VA patients. Significant correlations between EEG discriminant scores, emergency admission measures, and post-trauma neuropsychological test scores validated the discriminant function as an index of severity of injury and a classifier of the extremes of severity.
Language: en
LA - en SN - 0895-0172 UR - http://dx.doi.org/ ID - ref1 ER -