TY - JOUR PY - 2005// TI - Cognitive performance and autonomic reactivity in abstinent drug abusers and nonusers JO - Experimental and clinical psychopharmacology A1 - Fishbein, Diana A1 - Hyde, Chris A1 - Eldreth, Diana A1 - London, Edythe D. A1 - Matochik, John A1 - Ernst, Monique A1 - Isenberg, Nancy A1 - Steckley, Stacey A1 - Schech, Barry A1 - Kimes, Alane SP - 25 EP - 40 VL - 13 IS - 1 N2 - In this study the authors compared the performance of abstinent drug abusers (n = 21) and nonuser control participants (n = 20) in neurocognitive and emotional functions by use of the Rogers Decision Making Task, Gambling Task, Emotional Stroop, impulsivity continuous performance task (CPT), and vigilance CPT. Skin conductance (SC) and heart rate (HR) monitoring was synchronized with task performance. Groups showed similar performance for vigilance, impulsivity, and emotional interference; however, drug abusers showed stronger SC responses. Drug abusers performed more poorly on the Gambling and Rogers Decision Making Tasks. When making risky decisions, drug abusers showed significantly less increase in SC activity than controls and exhibited lower HRs throughout performance on all tasks. In conclusion, complex tasks involving decision making, sensitivity to consequences, and emotional regulation discriminated between drug abusers and controls.

Language: en

LA - en SN - 1064-1297 UR - http://dx.doi.org/10.1037/1064-1297.13.1.25 ID - ref1 ER -