TY - JOUR PY - 1999// TI - Colchicine poisoning: report of a fatal case with body fluid and post-mortem tissue analysis by high-performance liquid chromatography JO - Biomedical chromatography A1 - Dehon, B. A1 - Chagnon, J. L. A1 - Vinner, E. A1 - Pommery, J. A1 - Mathieu, D. A1 - Lhermitte, M. SP - 235 EP - 238 VL - 13 IS - 3 N2 - A case involving a suicide by the ingestion of colchicine tablets is presented. Liquid chromatography has been used to measure the drug level in blood and in post-mortem tissues of the patient (a 42-year-old man). Plasma concentration 24 h after ingestion was 4.5 ng/mL. On autopsy, the kidney showed the highest concentration (396 ng/g). High concentrations were also found in the liver (347 ng/g) and heart (334 ng/g). Low concentrations were detected in the lung (58 ng/g), muscle (10 ng/g) and brain (5 ng/g).
Language: en
LA - en SN - 0269-3879 UR - http://dx.doi.org/10.1002/(SICI)1099-0801(199905)13:3<235::AID-BMC827>3.0.CO;2-N ID - ref1 ER -