TY  - JOUR
PY  - 1999//
TI  - Use of phenothiazines as sedatives in children: what are the risks?
JO  - Drug safety
A1  - Dyer, K. S.
A1  - Woolf, A. D.
SP  - 81
EP  - 90
VL  - 21
IS  - 2
N2  - Phenothiazines have been widely used for their antiemetic, antipsychotic and sedative properties for many years. The introduction of alternative agents for paediatric sedation has led to the re-evaluation of phenothiazines as paediatric sedatives. Newer agents, such as fentanyl and midazolam, have short half-lives and reversal agents are available. Therefore these agents may offer comparable therapeutic efficacy with a better safety profile in young children. Reports of sudden infant death syndrome in children receiving a phenothiazine-containing syrup for symptoms of upper respiratory infection means that the outpatient use of these compounds in very young infants is not recommended.<p /> <p>Language: en</p>
LA  - en
SN  - 0114-5916
UR  - http://dx.doi.org/
ID  - ref1
ER  -