TY  - JOUR
PY  - 2000//
TI  - Effects of acute ethanol on indices of cognitive-behavioral performance in rats
JO  - Alcohol
A1  - Popke, E. J.
A1  - Allen, S. R.
A1  - Paule, M. G.
SP  - 187
EP  - 192
VL  - 20
IS  - 2
N2  - The present experiment examined the effects of ethanol on several complex operant behaviors in rats. Tasks included: temporal response differentiation (TRD) to assess timing behavior; differential reinforcement of low response rates (DRL) to assess timing and response inhibition; incremental repeated acquisition (IRA) to assess learning; conditioned position responding (CPR) to assess auditory, visual, and position discrimination; and progressive ratio (PR) to assess motivation. Ethanol (0.0, 0.5, 1.0, 1.5, 2.0, and 3.0 g/kg via orogastric gavage) reduced accuracy and/or percent task completed for the TRD, DRL, and CPR tasks. For CPR, this reduction was accompanied by a reduction in response rates. Ethanol also reduced response rates on the PR task. There were no effects of ethanol on IRA performance. These data suggest that ethanol can selectively impair performance on cognitive-behavioral tasks and that these effects can occur at doses that do not affect the subjects' ability to respond.<p /> <p>Language: en</p>
LA  - en
SN  - 0741-8329
UR  - http://dx.doi.org/
ID  - ref1
ER  -