TY  - JOUR
PY  - 2012//
TI  - The young brain and concussion: Imaging as a biomarker for diagnosis and prognosis
JO  - Neuroscience and biobehavioral reviews
A1  - Toledo, E.
A1  - Lebel, A.
A1  - Becerra, L.
A1  - Minster, A.
A1  - Linnman, C.
A1  - Maleki, N.
A1  - Dodick, D. W.
A1  - Borsook, D.
SP  - 1510
EP  - 1531
VL  - 36
IS  - 6
N2  - Concussion (mild traumatic brain injury (mTBI)) is a significant pediatric public health concern. Despite increased awareness, a comprehensive understanding of the acute and chronic effects of concussion on central nervous system structure and function remains incomplete. Here we review the definition, epidemiology, and sequelae of concussion within the developing brain, during childhood and adolescence, with current data derived from studies of pathophysiology and neuroimaging. These findings may contribute to a better understanding of the neurological consequences of traumatic brain injuries, which in turn, may lead to the development of brain biomarkers to improve identification, management and prognosis of pediatric patients suffering from concussion.<p />  <p>Language: en</p>
LA  - en
SN  - 0149-7634
UR  - http://dx.doi.org/10.1016/j.neubiorev.2012.03.007
ID  - ref1
ER  -