TY  - JOUR
PY  - 2000//
TI  - Acute poisoning with industrial products
JO  - Revue du praticien, La
A1  - Garnier, R.
SP  - 377
EP  - 384
VL  - 50
IS  - 4
N2  - Poisonings with industrial products represent approximately 7% of the cases reported to the poison centres. Ingestion of petroleum distillates induces irritation of the gastrointestinal tract, central nervous system depression and aspiration pneumonitis which may be severe; treatment is mainly supportive. Ethylene and diethylene glycol poisonings produce central nervous system depression, anion gap metabolic acidosis, osmolar gap and acute tubular necrosis; in severe cases, hypocalcaemia, cerebral oedema and heart failure may be observed; treatment often associates supportive measures, haemodialysis and administration of competitive inhibitors of alcohol dehydrogenase (ethanol or 4-methylpyrazole). Glycol ethers induce central nervous system depression and metabolic acidosis; in addition, ethylene glycol monobutyl ether produces haemolysis; monomethyl and monoethyl ethers are responsible for bone marrow and lymphoid organ toxicity, they adversely affect spermatogenesis and are teratogens.<p /> <p>Language: fr</p>
LA  - fr
SN  - 0035-2640
UR  - http://dx.doi.org/
ID  - ref1
ER  -