TY  - JOUR
PY  - 2012//
TI  - Prevalence of Cervical Cord Compression and its Association with Physical Performance in a Population-based Cohort in Japan: The Wakayama Spine Study
JO  - Spine
A1  - Nagata, Keiji
A1  - Yoshimura, Noriko
A1  - Muraki, Shigeyuki
A1  - Hashizume, Hiroshi
A1  - Ishimoto, Yuyu
A1  - Yamada, Hiroshi
A1  - Takiguchi, Noboru
A1  - Nakagawa, Yukihiro
A1  - Oka, Hiroyuki
A1  - Kawaguchi, Hiroshi
A1  - Nakamura, Kozo
A1  - Akune, Toru
A1  - Yoshida, Munehito
SP  - 1892
EP  - 1898
VL  - 37
IS  - 22
N2  - Study Design. A population-based MRI study of the cervical spine.Objective. This study was undertaken in order to investigate the prevalence of cervical cord compression (CCC) and to examine the association between CCC and physical performance measures in a population-based cohort established in Japan.Summary of Background Data. Population-based cohort studies of the prevalence of CCC, although essential for clarification of the prevalence of slowly progressive disease and specification of the time of incidence of CCC, are not available.Methods. This cross-sectional study was performed as a part of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study, a large-scale population-based cohort study in Japan. From 1,011 inhabitants who underwent magnetic resonance imaging (MRI) examinations, images of the cervical spine of 977 subjects (324 men, 653 women, mean age 66.4 years) were evaluated. CCC was assessed by sagittal T2-weighted MRI, and was defined as spinal cord compression. The prevalence of CCC and its association with myelopathic signs (hyperreflexia of the patellar tendon, and Hoffmann and Babinski reflexes) were examined. In addition, physical performance measures (grip and release test (GRT), grip strength, 6-m walking time, step length, chair-stand time (CST), and one-leg standing time) were tested.Results. The prevalence of CCC was 24.4%, and was significantly higher in men (29.3% in men, 21.9% in women, P = 0.011). The prevalence of CCC was higher with increasing age in both genders. CCC was not significantly associated with any myelopathic signs, but was significantly associated with GRT, 6-m walking time, step length, and CST.Conclusion. In the present MRI study, the prevalence of CCC was examined. The present results indicate that CCC correlates with physical performance measures from an early stage of the disease before myelopathic signs appear.<p />  <p>Language: en</p>
LA  - en
SN  - 0362-2436
UR  - http://dx.doi.org/10.1097/BRS.0b013e31825a2619
ID  - ref1
ER  -