TY - JOUR PY - 2012// TI - Motor vehicle accidents: How should cirrhotic patients be managed? JO - World journal of gastroenterology A1 - Kawaguchi, Takumi A1 - Taniguchi, Eitaro A1 - Sata, Michio SP - 2597 EP - 2599 VL - 18 IS - 21 N2 - Motor vehicle accidents (MVAs) are serious social issues worldwide and driver illness is an important cause of MVAs. Minimal hepatic encephalopathy (MHE) is a complex cognitive dysfunction with attention deficit, which frequently occurs in cirrhotic patients independent of severity of liver disease. Although MHE is known as a risk factor for MVAs, the impact of diagnosis and treatment of MHE on MVA-related societal costs is largely unknown. Recently, Bajaj et al demonstrated valuable findings that the diagnosis of MHE by rapid screening using the inhibitory control test (ICT), and subsequent treatment with lactulose could substantially reduce the societal costs by preventing MVAs. Besides the ICT and lactulose, there are various diagnostic tools and therapeutic strategies for MHE. In this commentary, we discussed a current issue of diagnostic tools for MHE, including neuropsychological tests. We also discussed the advantages of the other therapeutic strategies for MHE, such as intake of a regular breakfast and coffee, and supplementation with zinc and branched chain amino acids, on the MVA-related societal costs.

Language: en

LA - en SN - 1007-9327 UR - http://dx.doi.org/10.3748/wjg.v18.i21.2597 ID - ref1 ER -